If you work in a company, in all likelihood, you will experience auto-locking of the computer by the security policy applied on your machine. This can be very irritating, especially when you need to play a video or run a slideshow indefinitely for an exhibition or at a promotional event.
I found a very nifty utility by Mike Langford, who moves the mouse cursor by 1 pixel every 30 seconds to mimic mouse movement by a human hand. This effectively prevents the screen from locking up, which is excellent.